Allergy experts no longer recommend diphenhydramine (Benadryl)
Cetirizine (Zyrtec) is a safer and more effective antihistamine
Pediatricians and allergists are no longer recommending diphenhydramine (Benadryl) for simple allergic reactions because of concerns over side effects, lack of efficacy compared to newer over-the-counter antihistamines, and potential risks from chronic use in adults.
This article from the
World Allergy Organization Journal, as well as subsequent reviews on
Medpage Today and
CNN
provide good summaries of the changes in recommendation.
For the majority of our patients, we recommend instead, a one time (daily) dose of cetirizine (Zyrtec):
- 5 mg for children 2-5 years old
- 10 mg for children 6+ years of age
Please remember that in cases of ANAPHYLAXIS, ALWAYS USE EMERGENCY EPINEPHRINE FIRST
(cetirizine is NOT a substitute).
Please call our office at 434-975-7777 if you have any specific questions or concerns about the change.